About Us2018-05-18T20:07:20+00:00

About Prometheus Research

For nearly 20 years, Prometheus Research has been known for delivering managed registry services and informatics consulting with an unflinching focus on translational research and national quality initiatives to accelerate discovery and improve care through the repurposing of high-quality health data. This focus has enabled Prometheus to become thought leaders in multidisciplinary and multisite research endeavors while supporting some of the most ambitious projects in biomedical research and healthcare. More importantly, it has enabled us to serve as the trusted coordinators and curators of data assets relied upon by thousands of researchers and millions of families affected by illness.

Our approach begins and ends with demonstrably high-quality data because no amount of bad data will ever be enough to advance medical research or clinical care. Prometheus employs a novel data quality assurance framework that serves as both a communication framework for discussing and defining what data will enter the registry and an implementation framework for declaring and monitoring data quality logic in our research data registry software. Our framework is designed to be consistent, collaborative, and iterative, ensuring an open dialogue between Prometheus and our partners about their evolving registry and research goals. We ensure our partners and their stakeholders can concentrate their energies on identifying insights and opportunities for improving care, knowing the growing data asset they are using is secure, trustworthy, and well managed.

When we’re not liberating fire from the gods to give to mankind, we’re developing open-source clinical research database and patient registry software that makes it easier to share and repurpose scientific data, clinical research databases, and to manage the process of scientific discovery. Why are we passionate about open-source tools for open science? Because some knowledge is too important not to share.


Leon Rozenblit, JD, PhD
Leon Rozenblit, JD, PhDFounder & CEO

Our Mission is to empower teams to securely harness complex, sensitive data in regulated environments.

Recent Press

Our Values

At Prometheus, integrity means a deep consistency between your beliefs and your behavior, as well as a consistency within your beliefs. That kind of integrity speaks to being a whole person and shows you stand for something and are proud of what you stand for. That kind of integrity is more than honesty, more than just saying things that are true. Integrity means that your character can be deduced from your actions and that your character is internally consistent.
At Prometheus, curiosity is critical. We are an adapting, learning organization, and curiosity is what makes someone successful in this rapidly changing environment. Innate curiosity is the desire to learn new things. It is something that is difficult to fake if you don’t have it. People at Prometheus are all genuinely curious about making things better for ourselves, for the people around us and for our customers. We all enjoy being on the steep portion of the learning curve.
We treat each other with respect and consideration due independent thinking beings. We are charitable in our assumptions of good intent and competence in all our communication with internal and external collaborators. We represent what is best about civil behavior by treating even the people we don’t yet know well as valued potential partners.
We do not rest on our success. Prometheus regularly applies new best practices from clinical research informatics, business process analysis, and user-centered design.

Our relentless focus on data quality and transparency ensures that every data element/record will be defensible and trustworthy across a variety of quality improvement and comparative effectiveness activities.

What Our Clients Say

When I think of all the different ways in which Prometheus has been helpful on my projects, it’s amazing that they were hired “just” to build software. That’s probably because they’ve helped overcome numerous research challenges that had nothing to do with actually building the system. Their ability to quickly deliver software and procedures that support changing research environments, coupled with their deep caring about the research itself, makes it easy for me to recommend them.
Jennifer Tjernagel, MS, Project Manager, Simons Foundation, Simons Variation in Individuals Project

Awards and Recognition

Prometheus Website Privacy Notice

Prometheus helps our clients collect highly sensitive information, often in regulated environments, and we take great care to protect the privacy of patients and study participants and as well as the confidentiality of our clients and users.

We also seek to be appropriately careful about the information we collect about visitors to this website. Any information we collect here is processed securely and is never shared with an outside entity. Read our full privacy policy here.